Apolipoprotein E Antibodies Affect the Retention of Passive Avoidance Memory in the Chick
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Apolipoprotein E Antibodies Affect the Retention of Passive Avoidance Memory in the Chick
Isoforms of apolipoprotein E (ApoE) have been implicated as risk factors in Alzheimer's disease. We have, therefore, examined the possible role of ApoE in memory formation, using a one-trial passive avoidance task in day-old chicks. Birds were trained on the task and then at various times pre or post-training were injected intracerebrally with anti-ApoE. Immunofluorescence staining demonstrated...
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ژورنال
عنوان ژورنال: Neural Plasticity
سال: 1998
ISSN: 2090-5904,1687-5443
DOI: 10.1155/np.1998.29